Hand Tossed, By the Slice, Made Fresh Daily!

  • Buttery Crust & Homemade Sauces
  • Made with The Finest Ingredients
  • Cheesesteaks & Hot Subs
  • Hamburgers, & Hot Dogs
  • Loaded Fries & Chili Fries
  • Battered & Bacon Stuffed Mushrooms
  • Catering, Parties, & Events
  • Gluten Free & Keto Friendly Options
  • Open Late with Delivery Available
Order Online See Menu

Tailgating? Meetings? Events?

No order is too big or too small!    We offer a wide variety of sub trays, wing platters, pizzas, pastas, drinks, etc.  DELIVERY AVAILABLE!!!  With as little as just 24 hours notice we can make your big day be a smash hit.  We will build you a party platter to handle ALL of your guests needs!  Just click on the button to call us and we will hook you up…

Order Catering ONLINE

The Passion for Pizza...

In 2016, Chris Efaw and Derrick Nunziante obtained the rights to the Main Slice building to share their love of pizza to the locals and tourists alike.

Two years later The Main Slice was chosen by locals as The Best Pizza along The Grand Strand!

Located off Ocean Drive on Main Street in North Myrtle Beach, Main Slice is North Myrtle Beach’s original slice bar. Offering a variety of pizza by the slice options, Phillies, Burgers, and more, we are your one stop destination for street food done right!

More About Us

Google Reviews

  • review rating 5  The food was very good especially the cheese steak. The prices aren't bad and the employees are nice. I would recommend this place.

    thumb Ryan Hoffman

    review rating 5  Since we can only do take out - we ordered an entire dinner to go for 6 of us...Now, Main Slice is very unassuming....not a fancy place....That said, their Italian food is exceptional! Thin crusted Pizza, awesome meatball grinders, the best appetizers!! All very affordable....all made to order! So, I would highly recommend The Main Slice as you new Main Pizza Place! Thanks guys!

    thumb Bob Keller

    review rating 5  I think I’ve only left a review one time in my life. Tonight I had to take the time to say how impressed I am with this restaurant. I had the opportunity to meet the owner Derrick. His kind hospitality was as excellent as the food. We tried the pepperoni pizza and dry rub wings, incredible!! We are very picky eaters and hard to impress. Glad we have a new go-to when we come to north myrtle. Their menu is very impressive can’t wait to try more items.

    thumb Joshua Weatherly
  • review rating 5  So glad to know you deliver directly to our neighborhood! Wonderful! Salad, wings and pizza, all perfect.

    thumb Paula Amador

    review rating 5  Great place it has fresh pizza right out the oven. Good amount of cheese but not too much! This is one of the most addictive food I ever ate!

    thumb Jette Nunziante

    review rating 5  First time customers tonight. The pizza was excellent! And the subs delicious! We will definitely be back!

    thumb Donna Johns
  • review rating 5  Best pizza around the area!! Definitely going back!! Heard the burgers were right on time too!!

    thumb Jamie Steele

    review rating 5  A great slice of pizza. It was hot and delicious

    thumb steve yekel

    review rating 5  Holy pizza!! We chose a local non-chain that delivered and it was FABULOUS. The Hillbilly was sooooo good but the supreme and meat lovers were delicious too! Bonus-we received our 3 pizzas in a much quicker time frame than expected! Thanks Main Slice!!

    thumb Kathy Reinke
  • review rating 5  Some of the best pizza in nmb for sure! Always happy with the pizza. Not as fast as chains if trying to get delivery.. it's worth the wait.

    thumb Bo Gilbert

    review rating 5  Some of the best pizza in nmb for sure! Always happy with the pizza. Not as fast as chains if trying to get delivery.. it's worth the wait.

    thumb Bo Gilbert

    review rating 5  Great food! We had a OG Philly and 2 slices of pizza! So good! The staff was super friendly also! Definitely recommend. Prices were great!

    thumb Amanda Worley
  • review rating 5  You've gotta try this place!! Staff was so cool, explaining all of the different pizzas. I got the mac & cheese and the southern hillbilly. Flavors are nuts on the hillbilly. Ranch base, bbq, pork, crushed jalapenos just crazy. M&C will fill you up!

    thumb Kyle Matson

    review rating 5  Good Pizza. Got the meat lovers. Good crust. One in our party got the sweet bbq boneless wings. Very good. The fries are meaty and delicious. Another in our party got the Philly Cheesesteak. Again, very good and large with plenty of cheese with Fries. Definitely worth the visit while on Ocean Drive.

    thumb Brian Wray

    review rating 5  First time customers from Cleveland Ohio! The new worker that took our food order was very friendly and recommended the southern hillbilly pizza. The pizza was absolutely FANTASTIC! Thanks for the great recommendation and the awesome atmosphere. The main slice couldn’t be in a cooler location either! It’s right next to the BEACH! Thanks the main slice our group of 4 absolutely loved the pizza and the experience. We would all 💯% come back again! A must try pizza joint in North Myrtle Beach!! 🍕 🔥 💣

    thumb David
  • review rating 5  I'm from Ohio and decided to stop in the main slice and was I delicious ! I had a single slice of buffalo chicken with the 4 poppers. They were bigger then what I thought so it was so filling. I walked 45 minutes from my vacation home and it was worth it. And the gentleman making the food was nice as soon as I walked in the door. And helpful. 5/5 would recommend 🌹

    thumb Kasandra Baker

The Best Piece You Will Ever Get!


Mon, Tue, & Wed: 4 pm – 10 pm
Thur: 11 am – 10 pm
Fri & Sat:  11 am – Midnight
Sun 11 am – 10 pm

Note: Seasonal Hours May Vary


209 Main St North Myrtle Beach, SC 29582

Order Online NOW!

It’s easy, fast, & secure!