Hand Tossed, By the Slice, Made Fresh Daily!

  • Buttery Crust & Homemade Sauces
  • Made with The Finest Ingredients
  • Cheesesteaks & Hot Subs
  • Hamburgers, & Hot Dogs
  • Loaded Fries & Chili Fries
  • Battered & Bacon Stuffed Mushrooms
  • Catering, Parties, & Events
  • Gluten Free & Keto Friendly Options
  • Open Late with Delivery Available
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Tailgating? Meetings? Events?

No order is too big or too small!    We offer a wide variety of sub trays, wing platters, pizzas, pastas, drinks, etc.  DELIVERY AVAILABLE!!!  With as little as just 24 hours notice we can make your big day be a smash hit.  We will build you a party platter to handle ALL of your guests needs!  Just click on the button to call us and we will hook you up…

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The Passion for Pizza...

In 2016, Chris Efaw and Derrick Nunziante obtained the rights to the Main Slice building to share their love of pizza to the locals and tourists alike.

Two years later The Main Slice was chosen by locals as The Best Pizza along The Grand Strand!

Located off Ocean Drive on Main Street in North Myrtle Beach, Main Slice is North Myrtle Beach’s original slice bar. Offering a variety of pizza by the slice options, Phillies, Burgers, and more, we are your one stop destination for street food done right!

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Google Reviews

  • review rating 5  I think I’ve only left a review one time in my life. Tonight I had to take the time to say how impressed I am with this restaurant. I had the opportunity to meet the owner Derrick. His kind hospitality was as excellent as the food. We tried the pepperoni pizza and dry rub wings, incredible!! We are very picky eaters and hard to impress. Glad we have a new go-to when we come to north myrtle. Their menu is very impressive can’t wait to try more items.

    thumb Joshua Weatherly

    review rating 5  So glad to know you deliver directly to our neighborhood! Wonderful! Salad, wings and pizza, all perfect.

    thumb Paula Amador

    review rating 5  Great place it has fresh pizza right out the oven. Good amount of cheese but not too much! This is one of the most addictive food I ever ate!

    thumb Jette Nunziante
  • review rating 5  First time customers tonight. The pizza was excellent! And the subs delicious! We will definitely be back!

    thumb Donna Johns

    review rating 5  Best pizza around the area!! Definitely going back!! Heard the burgers were right on time too!!

    thumb Jamie Steele

    review rating 5  A great slice of pizza. It was hot and delicious

    thumb steve yekel
  • review rating 5  Holy pizza!! We chose a local non-chain that delivered and it was FABULOUS. The Hillbilly was sooooo good but the supreme and meat lovers were delicious too! Bonus-we received our 3 pizzas in a much quicker time frame than expected! Thanks Main Slice!!

    thumb Kathy Reinke

    review rating 5  Some of the best pizza in nmb for sure! Always happy with the pizza. Not as fast as chains if trying to get delivery.. it's worth the wait.

    thumb Bo Gilbert

    review rating 5  Some of the best pizza in nmb for sure! Always happy with the pizza. Not as fast as chains if trying to get delivery.. it's worth the wait.

    thumb Bo Gilbert
  • review rating 5  Great food! We had a OG Philly and 2 slices of pizza! So good! The staff was super friendly also! Definitely recommend. Prices were great!

    thumb Amanda Worley

    review rating 5  First time customers from Cleveland Ohio! The new worker that took our food order was very friendly and recommended the southern hillbilly pizza. The pizza was absolutely FANTASTIC! Thanks for the great recommendation and the awesome atmosphere. The main slice couldn’t be in a cooler location either! It’s right next to the BEACH! Thanks the main slice our group of 4 absolutely loved the pizza and the experience. We would all 💯% come back again! A must try pizza joint in North Myrtle Beach!! 🍕 🔥 💣

    thumb David

The Best Piece You Will Ever Get!


Mon, Tue, & Wed: 4 pm – 10 pm
Thur: 11 am – 10 pm
Fri & Sat:  11 am – Midnight
Sun 11 am – 10 pm

Note: Seasonal Hours May Vary


209 Main St North Myrtle Beach, SC 29582

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