Hand Tossed, By the Slice, Made Fresh Daily!

  • Buttery Crust & Homemade Sauces
  • Made with The Finest Ingredients
  • Cheesesteaks & Hot Subs
  • Hamburgers, & Hot Dogs
  • Loaded Fries & Chili Fries
  • Battered & Bacon Stuffed Mushrooms
  • Catering, Parties, & Events
  • Gluten Free & Keto Friendly Options
  • Open Late with Delivery Available
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Tailgating? Meetings? Events?

No order is too big or too small!    We offer a wide variety of sub trays, wing platters, pizzas, pastas, drinks, etc.  DELIVERY AVAILABLE!!!  With as little as just 24 hours notice we can make your big day be a smash hit.  We will build you a party platter to handle ALL of your guests needs!  Just click on the button to call us and we will hook you up…

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The Passion for Pizza...

In 2016, Chris Efaw and Derrick Nunziante obtained the rights to the Main Slice building to share their love of pizza to the locals and tourists alike.

Two years later The Main Slice was chosen by locals as The Best Pizza along The Grand Strand!

Located off Ocean Drive on Main Street in North Myrtle Beach, Main Slice is North Myrtle Beach’s original slice bar. Offering a variety of pizza by the slice options, Phillies, Burgers, and more, we are your one stop destination for street food done right!

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Google Reviews

  • review rating 5  Delicious pizza! Lots of options for sauces and toppings. We did pick up. Food was ready in 30 minutes and was hot and fresh.

    thumb Jen & Ray Dunham

    review rating 5  Great Pizza. I haven't been adventurous enough to try some of the off the wall pizzas they offer.

    thumb Kathy Poole

    review rating 5  Fantastic pizza right on the beach! Font hesitant to great a couple of ready to go slices from there display! Always fresh and delicious and with 7 to 8 flavors always ready you won't be disappointed Here! The service has always been fast and friendly and in the more than a dozen times I have eaten here it has always been a 5 star experience!

    thumb James Polino
  • review rating 5  Delicious pizza with good crust and hot, fresh toppings. Best we’ve had at the beach in 20+ years coming.

    thumb Sheila Richardson

    review rating 5  Ordered Calzones for dinner and were delivered in no time, excellent service and delicious food. We will be eating the leftovers again tomorrow. Thank you, we definitely will be ordering again

    thumb Rose Dougherty

    review rating 5  Ordered a Southern Hillbilly and Margherita Pizzas. Both very good and will eat here again. They have daily specials and pizza by the slice as well. Very easy call ahead and pick up from the beach as its a 5 minute walk.

    thumb randy blankinship
  • review rating 5  This cheesesteak challenge, is a challenege, and my novel is a good read 🤣🤣🤣 SOOO, the wife and I went to Main Slice on Main Street in North Myrtle. (7 out of 10 for you skimmers) It is a small restaurant about a half a block from our sandy beaches in North Myrtle and if quite enough, you can hear the waves crashing. Everyone was friendly, smiling and a very pleasant atmosphere. Even the customers were just as cheery. A very good positive vibe was going on when we visited. The CHALLENGE requires me to order a "cheesesteak" .....so I ordered a Philly cheese steak with steak, provolone, no peppers, no mayo. We also ordered some other food, and I will get to that in a minute. After a short wait, our food was done. The gentleman brought us the cheese steak wrapped in foil at the outside seating. Note, I did not notice any inside seating, so looks more like a grab and go location. After opening the cheesesteak, the cheese was gooey and looked sooo delicious. Plenty of meat and the bun looked sooo good.....this is hard to say because I normally eat Keto, and the bun is not Keto, not even close. Lol. I took the 1st bite.. wow.. I then realized I MESSED UP..... I messed up because this is not Keto, and WOW I wanted to eat the whole thing right away. I also messed up because normally a cheesesteak is greasy and I didn't add the mayo, due to not wanting excess grease and mayo and just a big mess.... without the mayo, left the cheesesteak a little dry, but that is my fault for assuming all cheesesteaks are created equal. I should have known better, since this is the exact reason I started this challenge!!!! We were able to eat the cheesesteak no problem. The consistency was superb, the bun slightly toasted, but still soft with a slight crunch. Everything was cooked to excellence and you can tell car went into making this sandwich. I personally give it a 7 out of 10 due to mainly the no mayo/dryness... again, I DO NOT LIKE GREASY FOOD, but didn't know what to expect. So heed my warning....add the mayo!!!!!!! This brings us to the "other" food. We ordered wings, fried with Teriyaki and baked with Carolina Sweet... or maybe it was the other way around. 🤣 anyway, we dipped in ranch and THEY WERE AMAZING!!! The temperature was hot, the sauce was flavorful and the taste of everything combined was a win...a 9 out of 10 for me. I could eat these all day!!!!! Lastly, we ordered an all meat pizza to go. As we left and walked down the street, I looked at the pizza 3 or 3 times. If I were not walking, I would taken a bite. 15 minutes later at home, I decided to take a bite...full from the other food, I pushed through!!!. OMG, ONE BITE WAS NOT ENOUGH!! I being full loved the taste so much I almost ate a huge slice. The sauce, the flavors, meat, everything was delicious!!!!. The pizza gets a 9 out or 10 for me....by the way... a few hours later, I reheated a slice and the half I left, and it was STILL AMAZING!!!! SUMMARY and for the skimmers... Cheesesteak - without mayo 7 of 10 (With mayo maybe pushed to an 8 or a 9) Wings - baked or fried 9 of 10 Pizza - 9 of 10.... reheated still 9 of 10

    thumb Ernest Rogers

    review rating 5  Main Slice Upon entering was greeted by all employees. Establishment was very clean and tidy. I ordered a Philly Cheesesteak with fried onions and provolone, hold the peppers. Cheesesteak was hot and fresh. Cheese and onions were perfectly mixed in and bun was slightly toasted. On a scale of 1-10 I give Main Slice Cheesesteak an 8. Next time I’ll add extra meat!

    thumb Heather Armstrong

    review rating 5  The food was very good especially the cheese steak. The prices aren't bad and the employees are nice. I would recommend this place.

    thumb Ryan Hoffman
  • review rating 5  Since we can only do take out - we ordered an entire dinner to go for 6 of us...Now, Main Slice is very unassuming....not a fancy place....That said, their Italian food is exceptional! Thin crusted Pizza, awesome meatball grinders, the best appetizers!! All very affordable....all made to order! So, I would highly recommend The Main Slice as you new Main Pizza Place! Thanks guys!

    thumb Bob Keller

    review rating 5  I think I’ve only left a review one time in my life. Tonight I had to take the time to say how impressed I am with this restaurant. I had the opportunity to meet the owner Derrick. His kind hospitality was as excellent as the food. We tried the pepperoni pizza and dry rub wings, incredible!! We are very picky eaters and hard to impress. Glad we have a new go-to when we come to north myrtle. Their menu is very impressive can’t wait to try more items.

    thumb Joshua Weatherly

    review rating 5  So glad to know you deliver directly to our neighborhood! Wonderful! Salad, wings and pizza, all perfect.

    thumb Paula Amador
  • review rating 5  Great place it has fresh pizza right out the oven. Good amount of cheese but not too much! This is one of the most addictive food I ever ate!

    thumb Jette Nunziante

    review rating 5  First time customers tonight. The pizza was excellent! And the subs delicious! We will definitely be back!

    thumb Donna Johns

    review rating 5  Best pizza around the area!! Definitely going back!! Heard the burgers were right on time too!!

    thumb Jamie Steele
  • review rating 5  A great slice of pizza. It was hot and delicious

    thumb steve yekel

    review rating 5  Holy pizza!! We chose a local non-chain that delivered and it was FABULOUS. The Hillbilly was sooooo good but the supreme and meat lovers were delicious too! Bonus-we received our 3 pizzas in a much quicker time frame than expected! Thanks Main Slice!!

    thumb Kathy Reinke

    review rating 5  Some of the best pizza in nmb for sure! Always happy with the pizza. Not as fast as chains if trying to get delivery.. it's worth the wait.

    thumb Bo Gilbert
  • review rating 5  Some of the best pizza in nmb for sure! Always happy with the pizza. Not as fast as chains if trying to get delivery.. it's worth the wait.

    thumb Bo Gilbert

    review rating 5  Great food! We had a OG Philly and 2 slices of pizza! So good! The staff was super friendly also! Definitely recommend. Prices were great!

    thumb Amanda Worley

    review rating 5  You've gotta try this place!! Staff was so cool, explaining all of the different pizzas. I got the mac & cheese and the southern hillbilly. Flavors are nuts on the hillbilly. Ranch base, bbq, pork, crushed jalapenos just crazy. M&C will fill you up!

    thumb Kyle Matson
  • review rating 5  Good Pizza. Got the meat lovers. Good crust. One in our party got the sweet bbq boneless wings. Very good. The fries are meaty and delicious. Another in our party got the Philly Cheesesteak. Again, very good and large with plenty of cheese with Fries. Definitely worth the visit while on Ocean Drive.

    thumb Brian Wray

    review rating 5  First time customers from Cleveland Ohio! The new worker that took our food order was very friendly and recommended the southern hillbilly pizza. The pizza was absolutely FANTASTIC! Thanks for the great recommendation and the awesome atmosphere. The main slice couldn’t be in a cooler location either! It’s right next to the BEACH! Thanks the main slice our group of 4 absolutely loved the pizza and the experience. We would all 💯% come back again! A must try pizza joint in North Myrtle Beach!! 🍕 🔥 💣

    thumb David

    review rating 5  I'm from Ohio and decided to stop in the main slice and was I delicious ! I had a single slice of buffalo chicken with the 4 poppers. They were bigger then what I thought so it was so filling. I walked 45 minutes from my vacation home and it was worth it. And the gentleman making the food was nice as soon as I walked in the door. And helpful. 5/5 would recommend 🌹

    thumb Kasandra Baker

The Best Piece You Will Ever Get!


Mon-Sat 11 am – 12 am
Sun 11 am – 10 pm

Note: Seasonal Hours May Vary


209 Main St North Myrtle Beach, SC 29582

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