Hand Tossed, By the Slice, Made Fresh Daily!

  • Buttery Crust & Homemade Sauces
  • Made with The Finest Ingredients
  • Cheesesteaks & Hot Subs
  • Hamburgers, & Hot Dogs
  • Loaded Fries & Chili Fries
  • Battered & Bacon Stuffed Mushrooms
  • Catering, Parties, & Events
  • Gluten Free & Keto Friendly Options
  • Open Late with Delivery Available
Order Online See Menu

Tailgating? Meetings? Events?

No order is too big or too small!    We offer a wide variety of sub trays, wing platters, pizzas, pastas, drinks, etc.  DELIVERY AVAILABLE!!!  With as little as just 24 hours notice we can make your big day be a smash hit.  We will build you a party platter to handle ALL of your guests needs!  Just click on the button to call us and we will hook you up…

Order Catering ONLINE

The Passion for Pizza...

In 2016, Chris Efaw and Derrick Nunziante obtained the rights to the Main Slice building to share their love of pizza to the locals and tourists alike.

Two years later The Main Slice was chosen by locals as The Best Pizza along The Grand Strand!

Located off Ocean Drive on Main Street in North Myrtle Beach, Main Slice is North Myrtle Beach’s original slice bar. Offering a variety of pizza by the slice options, Phillies, Burgers, and more, we are your one stop destination for street food done right!

More About Us

Google Reviews

  • 5 star review  Great pizza! Thin crust and lots of toppings. I love their salads too! Plan to eat outside!

    thumb Amanda Neice
  • 5 star review  Tried a piece of the Ocean Drive and Southern Hillbilly, both were great. Kids loved the pizza also. Will stop by next time we are in NMBeach.

    thumb Terence Coveney
  • 5 star review  Food was excellent

    thumb Eddie Schrum
  • 5 star review  Excellent Supreme style pizza and the antipasto salad was equally delicious !!

    thumb David Armstrong
  • 5 star review  Awesome wings!!!

    thumb Graham Odom
  • 5 star review  We recently ordered pizza from you. We got the southern hillbilly..the ocean drive..pepperoni for the kids and garlic parm bites. Everything was fantastic ! Best pizza I've had in a long time. We look forward to ordering from you next year when we vacation in NMB again.

    thumb Charlene Kramer
  • 5 star review  Pizza was incredible! Ordered delivery and it showed up way earlier than expected. Blown away by the crust flavor and texture. Tried three different pies (one being a custom build) and we love them all. We also ordered way too much (huge portions!).

    thumb Phil Everett
  • 5 star review  Huge slices, taste great , best pizza we've had here at the beach . And we have tried quite a few.

    thumb Rob Drake
  • 5 star review  Place is awesome. Tried many different specialty pizzas and liked every one

    thumb Frank Burrier
  • 5 star review  Delicious pizza! Lots of options for sauces and toppings. We did pick up. Food was ready in 30 minutes and was hot and fresh.

    thumb Jen & Ray Dunham

The Best Piece You Will Ever Get!


Sun – Thu 11 am – 10 pm
Fri & Sat 11 am – 12  am

Note: Seasonal Hours May Vary


209 Main St North Myrtle Beach, SC 29582

Order Online NOW!

It’s easy, fast, & secure!